Ann Arbor-based RetroSense, a private, clinical-stage biotechnology company focused on novel gene therapy approaches to restore vision in patients suffering from blindness, was acquired by leading global pharmaceutical company Allergan for $60 million. The acquisition will further the commercialization of RetroSense’s RST-001, a novel gene therapy for the potential treatment of Retinitis Pigmentosa (RP).

Ann Arbor SPARK has provided support to RetroSense since 2010, including investment through the Michigan Pre-Seed Capital Fund. The funding RetroSense received from the Michigan Pre-Seed Capital Fund, which is supported by the 21st Century Jobs Fund and the Michigan Economic Development Corp., was the first outside equity raised by the company and was a match to the grant it received from the National Institutes of Health.
“Investment from the Michigan Pre-Seed Capital Fund allowed RetroSense to meet key milestones the led to additional outside investment,” said Skip Simms, Ann Arbor SPARK senior vice president and Michigan Pre-Seed Capital Fund manager. “The company’s further success and acquisition by Allergan enabled it to return the pre-seed investment to the Fund — the largest ever return. RetroSense clearly illustrates the importance of the state and public sector in nurturing startups.”
In addition to Michigan Pre-Seed Capital Fund support, Ann Arbor SPARK provided RetroSense grants for pre-clinical and clinical trial planning, corporate identity, branding, and website, and study design and validation. RetroSense was a client at SPARK’s accelerator, which is funded by the by the Ann Arbor/Ypsilanti SmartZone (LDFA), since 2012. Recently, the company was able to complete market research through SPARK’s internship program.